Prototype 2 is an open-world action game published by Activision and developed by Radical Entertainment. It's a direct sequel to Prototype and was announced at the 2010 Spike Video Game Awards. The events of Prototype 2 takes place in New York City, now known as New York Zero (NYZ), following Sgt. James Heller on his quest to destroy Alex Mercer, after having lost everything and everyone he loved to the Blacklight virus.

Infamous: Festival of Blood is an action-adventure video game developed by Sucker Punch Productions for the PlayStation 3 video game console. Festival of Blood is a standalone expansion in the Infamous series based on the Infamous 2 engine and map but does not require a copy of Infamous 2 in order to play. The story is set aside from the canon aspect of the Infamous series, being a spoof told by the main protagonist's friend Zeke Dunbar. The game features new characters, powers and comes with a new comic cutscene creation for the main game Infamous 2 '​s user-generated content, as well as support for the PlayStation Move controller. Unlike previous games, the game does not feature karmic choices on missions due to Cole's vampire state.

Infamous: Second Son, a PlayStation 4 exclusive , brings you an action adventure game where surrounded by a society that fears them, superhumans are ruthlessly hunted down and caged by the Department of Unified Protection. Step into a locked-down Seattle as Delsin Rowe, who has recently discovered his superhuman power and is now capable of fighting back against the oppressive DUP. Enjoy your power as you choose how you will push your awesome abilities to the limit and witness the consequences of your actions as they affect the city and people around you.